Boston, Massachusetts, 02210
Job description
Analytical Chemist
Boston, MA
$35-40/hr
The Analytical Chemist will become a member of the Mass Spectrometry team. This position involves the comprehensive development, validation, and execution of LC-MS methods spanning a wide array of modalities, including primary metabolites, small molecules, intricate peptides, and whole proteins.
Key Responsibilities of the Analytical Chemist:
- Method Development: Create and refine reliable LC-MS/MS methods to quantify and characterize small molecules, specialized metabolites, peptides, and proteins.
- Instrumentation: Operate, maintain, and troubleshoot cutting-edge mass spectrometers, particularly Thermo Orbitrap (Exploris/Lumos) and Triple Quadrupole (TSQ) systems.
- Data Processing: Leverage advanced software tools (such as TraceFinder, Compound Discoverer, Proteome Discoverer, or Skyline) to analyze complex datasets and provide meaningful insights to project teams.
- Independent Execution: Oversee multiple projects concurrently, from the design of experiments and preparation of samples to the final reporting of data, working with minimal oversight.
- Cross-Functional Collaboration: Collaborate with metabolic engineers, synthetic biologists, and automation engineers to incorporate analytical assays into high-throughput workflows.
Qualifications for the Analytical Chemist:
- Master’s degree in Analytical Chemistry, Biochemistry, or a close relevant discipline; alternatively, a Bachelor’s degree accompanied by over 3 years of pertinent industrial experience.
- Practical experience with high-resolution accurate mass (HRAM) and MRM/SRM protocols.
- Proficient in various chromatography techniques including RPLC, HILIC, and Ion Exchange.
- Acquainted with sample preparation methods for biological matrices (including SPE, SLE, and protein precipitation).
- Strong problem-solving skills to address hardware complications and analyze challenging biological data.
- Exceptional written and verbal communication abilities, capable of conveying complex analytical results to non-specialist audiences.
STEMHUNTER is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, gender identity, and gender expression), national origin, age, disability, genetic information, veteran status, or any other status protected by applicable federal, state, or local law. We comply with all applicable equal employment opportunity and affirmative action regulations.
